Yes, go ahead and grab that cup of joe, or two, or more. Doing so may improve your health and help you live longer, suggests new research. In a new observational study involving close to 20,000 individuals, people who consumed at least four cups of coffee daily had a 64% lower risk of early death compared to those who never or rarely consumed coffee. ＿＿（28）＿＿ These findings echo the recent results of another large observational study, which found that coffee drinkers appear to live longer, regardless of whether they consume regular or decaf coffee. Coffee has also been shown to reduce the risk of many diseases, including type 2 diabetes, liver disease, colorectal cancer, Alzheimer's and skin cancer, too. "Coffee is loaded with antioxidants," said Joe DeRupo, a spokesman for the National Coffee Association. "Many are naturally occurring antioxidants found in the coffee bean, while others are created during the roasting process. ＿＿（29）＿＿" While coffee consumption may appear to be healthful for many, others should proceed with caution. Pregnant women, for example, should cautiously limit their intake of caffeinated coffee. "Current evidence suggests that consuming moderate amounts of caffeine up to 200 mg per day, the amount in a 12-ounce cup of coffee, is not associated with increased risks for miscarriage or preterm birth," said Dr. Joseph Wax, chair of the American College of Obstetricians and Gynecologists' Committee on Obstetric Practice. "＿＿（30）＿＿" Additionally, "there is insufficient evidence to draw any conclusion regarding the effects of caffeine on fetal growth." ＿＿（31）＿＿ "Caffeine is an aggravator and accelerator of one's heart rate," said Dr. Vince Bufalino, a spokesman for the American Heart Association and senior vice president and senior medical director of Cardiology-AMG, Advocate Health Care, in Naperville, Illinois. "Those with atrial fibrillation or hypertension should limit their caffeine intake. One to two cups daily is probably fine, but if you are sensitive, you should restrict all caffeine."