High blood pressure has been of great concern for many people nowadays. It places a severe ＿＿（36）＿＿ on the heart, blood vessels, and kidneys. It may ＿＿（37）＿＿ cause the heart to enlarge and become thickened. In some cases, the heart may fail. High blood pressure can also cause the blood vessels to overstretch, weaken, or burst; a ＿＿（38）＿＿ blood vessel in the brain can cause a stroke or even paralysis. The third and most serious ＿＿（39）＿＿ related to high blood pressure is kidney failure. When the kidneys cease to function, they no longer ＿＿（40）＿＿ waste products. The result of kidney failure may be serious illness, or even death.