所謂呼吸鏈偶合氧化磷酸化（coupling oxidative phosphorylation），意指以下那兩個反應伴隨（偶合）發生：①$\text{NADH}+\frac{1}{2}{\text{O}}_2+{\text{H}}^{+}\to {\text{H}}_2\text{O}+{\text{NAD}}^{+}$ ②$\text{Pyruvate}+\text{NADH}+{\text{H}}^{+}\to \text{lactate}+{\text{NAD}}^{+}$ ③$\text{ADP}+{\text{P}}_i+{\text{H}}^{+}\to \text{ATP}+{\text{H}}_2\text{O}$ ④$\text{Creatine phosphate}+\text{ADP}\to \text{ATP}+\text{creatine}$