Since March 2020, routine childhood immunization services have been disrupted on a global scale that may be unprecedented since the inception of expanded programs on immunization in the 1970s. Fifty-three percent of the 129 countries where data were available reported moderate-to-severe disruptions, or a total ＿＿（41）＿＿ of vaccination services during March-April 2020. "Immunization is one of the most powerful and fundamental disease prevention tools in the history of public health," said Dr. Tedros Adhanom Ghebreyesus, WHO Director-General. "Disruption to immunization programmes from the COVID-19 pandemic ＿＿（42）＿＿ to unwind decades of progress against vaccine-preventable diseases like measles." "At the 4 June Global Vaccine Summit in London, donors will ＿＿（43）＿＿ their support to the Vaccine Alliance to sustain and accelerate this lifesaving work in some of the most vulnerable countries. From the bottom of my heart, I urge donors to fully fund the Alliance." The reasons for disrupted services ＿＿（44）＿＿ . Some parents are reluctant to leave home because of restrictions on movement, lack of information or because they fear ＿＿（45）＿＿ with the COVID-19 virus. And many health workers are unavailable because of restrictions on travel, or redeployment to COVID response duties, as well as a lack of protective equipment.