下列抗心律不整藥物中,可能導致心電圖QT interval延長,引起心律不整副作用之機制為何?
Apropafenone,抑制鈉離子通道,但會導致INa slow inactivation,產生delayed afterdepolarizations
Bsotalol,拮抗β-adrenergic receptor,產生delayed afterdepolarizations
Camiodarone,抑制鉀離子通道,尤其是IKr,產生early afterdepolarizations正確答案
Dadenosine,拮抗A1 receptor,抑制鉀離子通道,產生early afterdepolarizations
答案與詳解
